Prescribing Safety Assessment (PSA) Practice Exam

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Which two components make up co-amoxiclav?

  1. Azithromycin and Clavulanic acid

  2. Amoxicillin and Clavulanic acid

  3. Ciprofloxacin and Amoxicillin

  4. Penicillin and Clavulanic acid

The correct answer is: Amoxicillin and Clavulanic acid

Co-amoxiclav is a combination antibiotic that consists of amoxicillin and clavulanic acid. Amoxicillin is a broad-spectrum penicillin antibiotic that effectively targets a variety of bacterial infections. However, some bacteria produce an enzyme called beta-lactamase, which can inactivate amoxicillin. Clavulanic acid acts as a beta-lactamase inhibitor, preventing certain bacteria from breaking down amoxicillin and thereby enhancing its effectiveness. The pairing of amoxicillin with clavulanic acid allows for a wider range of bacterial pathogens to be effectively treated, particularly those that have developed resistance mechanisms. This synergistic effect is what makes co-amoxiclav a valuable option in treating infections that may not respond to amoxicillin alone. Understanding this combination is essential for safe and effective antibiotic prescribing practices, as it highlights the importance of combating antibiotic resistance while still addressing infections effectively.