Prescribing Safety Assessment (PSA) Practice Exam

What is the recommended dosage for PRN analgesia?

1. Paracetamol 500mg QDS

2. Paracetamol 1g QDS

3. Ibuprofen 1g QDS

4. Codeine 30mg QDS

The correct answer is: Paracetamol 1g QDS

The recommended dosage for PRN analgesia often prioritizes safety and effectiveness, especially when considering paracetamol, which is commonly used for pain relief. The option specifying 1g of paracetamol administered four times a day (QDS) aligns with recommended guidelines for adult dosing. Paracetamol has a maximum single dose of 1g and a recommended maximum daily dose of 4g for most adults. This dosing schedule allows for effective pain management while minimizing the risk of adverse effects, such as liver toxicity that could occur with excessive intake. In contrast, the option of 500mg QDS falls short of offering adequate pain relief for patients who may require higher dosages for chronic or severe pain. Similarly, ibuprofen at 1g QDS may exceed safe limits for other patients, particularly those with risk factors for gastrointestinal or renal issues. The option of codeine, while effective for certain pain types, involves considerations of dependency and side effects like sedation. Therefore, the 1g of paracetamol QDS represents a balance of efficacy and safety for PRN analgesia in most general adult patients.