Prescribing Safety Assessment (PSA) Practice Exam

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What is indicated by a CHA2DS2-VASc score of 4?

  1. Low risk of stroke

  2. Moderate risk of stroke

  3. High risk of stroke

  4. No risk of stroke

The correct answer is: High risk of stroke

A CHA2DS2-VASc score of 4 indicates a high risk of stroke. This scoring system is used to assess the risk of stroke in patients with atrial fibrillation. Each component of the score—such as heart failure, hypertension, age, diabetes, and prior strokes—contributes to the overall risk assessment. A score of 4 signifies that the patient has multiple risk factors present, which escalates their likelihood of experiencing a stroke. The higher the score, the greater the risk, and a score in the 4 range typically leads to recommendations for anticoagulation therapy to mitigate that risk. In this context, low, moderate, or no risk would suggest fewer or less severe risk factors affecting stroke likelihood, which does not apply with a score of 4.