Prescribing Safety Assessment (PSA) Practice Exam

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In patients with asthma, which antihypertensive should be avoided due to potential respiratory complications?

ACE Inhibitors
Diuretics
Beta Blockers
Calcium Channel Blockers

The correct answer is: Beta Blockers

In patients with asthma, beta blockers should be avoided due to the potential for respiratory complications. This class of medication can provoke bronchospasm, which is particularly concerning for individuals with asthma, as it can worsen their condition and lead to difficulty breathing. Beta blockers work by blocking beta-adrenergic receptors, which are also involved in bronchial dilation. For asthmatic patients, this blockage can lead to constriction of the airways, thus exacerbating their symptoms and potentially leading to severe asthma attacks. The other antihypertensive options do not pose the same risk. ACE inhibitors and diuretics do not typically affect the airways in a negative manner, making them safer alternatives for patients with asthma. Calcium channel blockers also do not significantly impact bronchial tone and are generally considered safe in these patients. Therefore, the avoidance of beta blockers in asthmatic individuals is based on their potential to induce respiratory complications.