Prescribing Safety Assessment (PSA) Practice Exam

In the context of suspected sepsis, the initial fluid management is critical for stabilizing the patient, and a fluid bolus of 500 ml is typically recommended. This volume is often used based on guidance from sepsis management protocols which stress the importance of early intravenous fluid resuscitation to improve tissue perfusion and support organ function.

Administering a bolus of 500 ml is a practical approach that balances the need for rapid correction of potential hypovolemia with the risk of fluid overload. This volume can help assess the patient’s response to fluid. If the patient's signs of hypotension, tachycardia, or altered mental status improve after this bolus, it can indicate the effectiveness of fluid resuscitation which is crucial in the early management of sepsis.

Other options, like a smaller bolus of 50 ml, may be insufficient in a septic patient, as they are likely already in a state of significant fluid deficit. A larger bolus of 1L might be appropriate in certain cases; however, the standard initial recommendation often starts at 500 ml, as it allows for careful monitoring of the patient's response before deciding on further fluid administration. Not initiating fluid management in a suspected sepsis scenario could lead to adverse